.
By Laurie Haan
Collection Overview
Abstract
The John L. Ubels Papers contain papers from Ubels’s career as a professor and scientific consultant. This collection consists of 1.5 linear feet of reports and published studies written between 1976 and 2008. Many of the reports were written for Alcon Laboratories, Ltd.
Scope and Contents of the Materials
The John L. Ubels Papers contain papers from Ubels’s career as a professor and scientific consultant. This collection consists of 1.5 linear feet of reports and published studies written between 1976 and 2008. Many of the reports were written for Alcon Laboratories, Ltd. Many papers were written on the subject of dry eyes and artificial tears.
Collection Historical Note
John L. Ubels was born in Modesto, California on June 9, 1952. He earned a Bachelor of Science degree from Calvin College, a Master of Science degree from the University of Michigan, and a PhD in animal physiology from Michigan State University. He later taught biology at Calvin College from 1995 to 2016.
Dr. Ubels taught human physiology and cell physiology during his time at Calvin University. He led an interim sailing course in Florida and an eye care service-learning interim course in Tijuana, Mexico. During his years at Calvin, he mentored 56 students in his research lab. He did extensive research for Alcon Research, Ltd. on ophthalmology, particularly dry eyes treatments. He did extensive testing for the development of Systane and Artificial Tears. Over the past 44 years, he has published 104 papers and chapters on every part of the eye of fish, amphibians and mammals, including humans. During his retirement, he teaches part time at the Michigan State University College of Human Medicine and is a guest scientist at the Van Andel Research Institute.
Biographical Note
Dr. Ubels taught human physiology and cell physiology during his time at Calvin University. He led an interim sailing course in Florida and an eye care service learning interim course in Tijuana, Mexico. During his years at Calvin, he mentored 56 students in his research lab. He did extensive research for Alcon Research Ltd. on opthmology, particularly dry eyes treatments. He did extensive testing for the development of Systane and Artifical Tears. Over the past 44 years, he has published 104 papers and chapters on every part of the eye of fish, amphibians and mammals, including humans. During his retirement, he teaches part time at the Michigan State University College of Human Medicine and is a guest scientist at the Van Andel Research Institute
Subject/Index Terms
Administrative Information
Repository:
Heritage Hall, Hekman Library
Access Restrictions:
<span style="color: rgb(16, 55, 93); font-family: Verdana, Arial, sans-serif; font-size: 12.96px;">Collection held in Heritage Hall; materials are not available for circulation</span>
Acquisition Source:
Gift of John L. Ubels
Acquisition Method:
Donation
Box and Folder Listing
Browse by Series:
[
Series 1: General Files],
[
Series 2: Published Articles],
[Series 3: Reports to Alcon Research, Ltd.],
[
All]
- Series 3: Reports to Alcon Research, Ltd.
- Box 3
- Folder 1: "Effect of Mussel Adhesive Protein on Corneal Epithelial Wound Healing" --- 1987
- Report submitted to Alcon Laboratories
- Folder 2: "All-Trans Retinoyl-Beta-Glucuronide for Treatment of Ocular Surface Disease" --- 1987
- Report submitted to Alcon Laboratories
- Folder 3: "Physiologic Efficacy of Artificial Tear Solutions --- 1995
- Report submitted to Alcon Laboratories
- Folder 4: "The Ocumer Polymer in an Artificial Tear Solution" --- 1997
- Report submitted to Alcon Laboratories
- Folder 5: "Biological Activity of Water-Soluble Acetretin Derivatives" --- 1997
- Report submitted to Alcon Laboratories
- Folder 6: "Stimulation of Ocular Surface Mucin Secretion by 15(S)-(HETE)" --- 1999
- Report submitted to Alcon Laboratories
- Folder 7: Reports to Alcon Research, Ltd. on Dry Eye Relief Research --- 2001
- Folder 8: "Testing of Artificial Tear Formulations" --- 2002
- Folder 9: "Effects of a Tear Formulation Containing Aminomethylpropanol and HP-guar at Varying pH on Cells in Culture and Rabbit Corneal Epithelium" --- 2003
- Report submitted to Alcon Research
- Folder 10: "Proliferation of Cells Exposed to AMP at Varying pH" --- 2004
- Folder 11: Reports to Alcon Research, Ltd. on Dry Eye Research --- 2005
- Folder 12: "Evaluation of Concepts for the Relief of Dry Eye Symptoms" --- 2006
- Report submitted to Alcon Research, Ltd.
- Folder 13: Reports to Alcon Research, Ltd. on Dry Eye Relief Research --- 2007
- Folder 14: "Evaluation ORB Ocular Emulsion Formulations" --- 2006
- Report submitted to Alcon Research, Ltd.
- Folder 15: "Pre-clinical Toxicologic Evaluation of FID 114675A - Revised" --- 2009
- Report submitted to Alcon Research, Ltd.
- Folder 16: "In Vitro Viability of Corneal Epithelial Cells Exposed to Forumlations Containing Hydroxypropyl Guar Galactomannan (HPGG)" --- 2007
- Folder 17: "Effect of Prolonged Exposure to Hydroxypropyl Guar Galactomannan in Combination with Polyquaternium-1 on the Permeability of Rabbit Corneal Epithelium" --- 2007
- Folder 18: "Toxicologic Evaluation of Contact Lens Solutions" --- 2008
- Folder 19: "Pre-Clinical Toxicologic Evaluation of Bis-amine Exploratory Formulations (14336-33A, B, C, D, E) --- 2009
- Folder 20: "Toxicologic Evaluation of Experimental Hydrogen Peroxide Lens Solutions" --- 2009
- Folder 21: "Pre-Clinical Toxicologic Evaluation of Bis-amine Compounds (AL-38571, AL-39586, AL-39503, Bis-Tris, Ultra AMP(AMP-95))" --- 2009
- Folder 22: "Evaluation of Experimental Contact Lens Solutions Containing H2O2" --- 2009
- Folder 23: "March 2010 Deliverable: Cytotoxicity Testing of Contact Lens Care Soluutions Using Lenses Cycled 10 Times" --- 2010
- Folder 24: "Investigation of Contact Lens, Storage Case, and Multipurpose Solution Interaction and their Effects on Corneal Epthelial Cells Using a Lens Overlay Model" --- 2010
- Folder 25: "Optimization of a Cellular Antioxidant Activity Assay for Use with Human Coreanl Epthelial Cells" --- 2010
- Folder 26: "Stratification of FTT Cells in Culture" --- 2010
- Folder 27: "Antioxidant Effects of Genistein in HBSS" --- 2011
- Folder 28: "Bioavailability and Activity of Various Antioxidants in Systane Ultra or Systane Balance" --- 2011
- Folder 29: "Toxicologic Evaluation of Protective Effect of Dry Eye Formulations Containing Hyaluronic Acid on Stratified Corneal Epithelial Cells" --- 2011
- Folder 30: "TNF-R1 and FADD mediate UVB-Induced activation of K+ Channels in corneal epithelial cells" --- 2016
- Folder 31: "Prevalence of Refractive Error and Need for Corrective Lenses in Medically Underserved Residents of Tijuana, Mexico" --- 2019
- Folder 32: "Patch-clamp Recording of K+ Current from Lacrimal Gland Duct Cells"
- Folder 33: Sjogren's Quarterly, "Do No Harm: Why Should You Avoid Benzalkonium Chloride-Containing Artificial Tears" --- 2020
- Folder 34: The CRISPR Journal, "Low-Density Lipoprotein Receptor-Related Protein 5-Deficient Rats Have Reduced Bone Mass and Abnornal Development of Retinal Vasculature" --- 2020
- Folder 35: Experimental Eye Research, "Structure and function of the retina of low-density lipoprotein receptor-related protein 5 (Lrp5)-deficient rats" --- 2022
Browse by Series:
[
Series 1: General Files],
[
Series 2: Published Articles],
[Series 3: Reports to Alcon Research, Ltd.],
[
All]
